Side effects, including cataracts and glaucoma, can occur after repeated use of hydrocortisone-containing products in the eyes. However, some antibiotic eyedrops and eardrops contain small amounts of hydrocortisone that are safe for short-term use only. Additionally, most hydrocortisone products are unsafe to use in or around the eyes. Hydrocortisone should only be used on the face if specifically recommended by a doctor because it can worsen the symptoms of certain skin conditions, such as some types of acne. Hydrocortisone should generally not be used inside the vagina or on the external genitalia, such as the penis or testicles, due to the risk of side effects. Rectal hydrocortisone is most often used to treat hemorrhoids, but it can also be used for conditions such as proctitis (inflammation of the rectum) and ulcerative colitis. However, hydrocortisone is not FDA-approved for these uses. Hydrocortisone can also be used to treat sunburn, redness of the skin, and skin swelling. Food and Drug Administration (FDA) has approved topical hydrocortisone for treating dermatitis and other skin conditions that cause itching, such as bug bites and psoriasis. The topical creams come in over-the-counter and prescription strengths, while the oral medications are only available by prescription. Hydrocortisone is available in multiple forms, including topical creams and ointments, oral tablets, and rectal creams and suppositories. Corticosteroids work within the body to block certain immune reactions that cause itching and inflammation (swelling). Hydrocortisone is a drug that belongs to a class of medications called corticosteroids.
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